Magnesium L-Threonate (CAS 778571-57-6)
NutraJagen Magnesium L-Threonate is a premium ingredient factory-supplied directly for high-standard global formulation requirements.
🧪 Technical Specs: Magnesium L-Threonate | White to Off-White Powder | Active Assay ≥98.0% (Magnesium 7.2%–8.3%).
📦 MOQ & Packaging: Min Order 1Kg | Standard 25Kg/Drum or Tailored Custom Packaging.
🌍 Global Compliance: Certified by ISO22000, HACCP, and HALAL to meet stringent international audits.
⚡ Supply Capacity: Factory-direct stable bulk supply. Active Stocks: 1,000Kg–2,000Kg available for immediate dispatch. Full COA/MSDS ready.
*Storage Notice: Store in tightly closed original container, protected from light. Free laboratory pilot samples available.
Magnesium L-Threonate (CAS 778571-57-6) Bulk Supply
Magnesium L-Threonate (CAS 778571-57-6) represents a targeted mineral chelate synthesized through the controlled reaction of L-threonic acid and bio-available magnesium sources, yielding a specialized complex with the empirical molecular formula C8H14MgO10. Conventional inorganic and organic magnesium compounds fail to cross the blood-brain barrier efficiently due to transport saturation kinetics; this precise L-threonate ligand structure facilitates elevated central nervous system absorption via specialized trans-endothelial carrier pathways. Industrial batch manufacturing controls enforce rigorous aqueous solubility thresholds exceeding 30 g/100 mL alongside low-hygroscopicity crystal engineering, eliminating common clumping issues during high-speed encapsulation and tableting. Designed primarily for premium neuro-cognitive dietary supplements, functional powder blends, and focus-enhancing beverage matrices, its high chemical compatibility prevents chelation conflict when combined with sensitive botanical extracts or B-vitamin complexes. Global nutraceutical brand owners leverage this factory-direct ingredient to secure stable batch-to-batch mineral density, eliminate raw material potency variance, and capture high-margin market share in brain health categories.
Core Health & Commercial Applications
Core Health & Physiological Mechanisms: Neuro-pharmacological trials establish that L-threonate molecules drive systemic elevation of brain magnesium concentrations significantly more effectively than chloride, citrate, or glycinate salts. Elevated cerebrospinal fluid magnesium ions increase synaptic density within hippocampal neural networks while enhancing N-methyl-D-aspartate (NMDA) receptor structural signaling pathways. Research shows that this specific chelate upregulates synaptic plasticity, supports long-term potentiation (LTP), reduces neuro-inflammatory oxidative stress, and regulates GABAergic neurotransmission to encourage restorative sleep architecture without causing osmotic gastrointestinal discomfort.
Targeted Industry Applications: R&D formulators incorporate this advanced compound across premier wellness product lines. Primary commercial delivery formats include cognitive-enhancement HPMC/gelatin capsules, brain-fog recovery sachets, direct-compression nootropic tablets, functional effervescent drink powders, calm-focused RTD liquid shots, and geriatric neurological support stick packs.
Technical Specifications (TDS)
| Parameter | Specification Standard | Test Method |
|---|---|---|
| Chemical Name | Magnesium L-Threonate | In-House Standard |
| CAS Registry Number | 778571-57-6 | CAS Index |
| Appearance | White to Off-White Fine Powder | Visual Inspection |
| Active Assay Purity | ≥ 98.0% (Calculated on Dry Basis) | HPLC / Complexometric Titration |
| Elemental Magnesium Content | 7.2% – 8.3% | AAS / ICP-OES |
| Loss on Drying | ≤ 1.5% | 105°C, 3 Hours |
| Heavy Metals (as Pb) | ≤ 10 ppm (Pb ≤1.5ppm, As ≤1.0ppm, Cd ≤0.5ppm, Hg ≤0.1ppm) | ICP-MS |
| Residual Solvents Control | Meets USP / EP Limits (Ethanol ≤5,000 ppm, Methanol ≤3,000 ppm) | GC-HS |
| Microbiological Profile | Total Plate Count <1,000 cfu/g; Yeast/Mold <100 cfu/g; E. coli / Salmonella: Negative | USP / AOAC Standards |
| Commercial Packaging | 25 Kg Net Weight Fiber Drum with Double PE Food-Grade Liners | Export Packaging Standard |
| Shelf Life | 24 Months when stored in original sealed packaging under cool, dry conditions | Real-Time Stability Protocol |
Formulation Processing Guidelines: Recommended active dosages range between 1,000 mg to 2,000 mg daily (delivering approximately 72 mg to 144 mg of elemental magnesium). Maintain production aqueous environment pH between 4.0 and 6.8 to preserve chelate stability during processing. Thermal stress testing confirms stability up to 80°C under moderate thermal pasteurization cycles. For liquid production runs, add powder during early liquid blending steps under constant mechanical agitation to ensure rapid dispersion.
Global Bulk Logistics Matrix
| Shipping Method | Suited Volume & Freight Cost | Logistics Service Details |
|---|---|---|
| Express Courier (FedEx/DHL/TNT) | < 50 kg | Higher Unit Cost | Door to Door delivery; 2–3 Business Days transit time; Ideal for samples, urgent pilot production runs, and bench-scale R&D. |
| Air Freight Cargo | 50 kg – 500 kg | Moderate Freight Cost | Airport to Airport; 3–5 Business Days transit time; Optimal balance between transport speed and commercial freight cost. |
| Ocean Sea Freight (FCL/LCL) | > 500 kg | Lowest Unit Freight Cost | Seaport to Seaport; 5–7 Days regional / 15–25 Days global transit; Maximum cost efficiency for full commercial factory orders. |
Technical & Commercial Advantages
NutraJagen brings more than 15 years of expertise in astaxanthin manufacturing and global supply, supported by a broad portfolio covering thousands of plant extract ingredients to service international health brands, contract manufacturers, and pharmaceutical distributors.
1. Natural Solutions: Focus on plant-based ingredients aligned with clean, sustainable, and health-oriented international concepts, securing traceable raw material streams and robust sustainability practices across all production steps.
2. Quality Management: In-house testing facility combined with independent third-party verification ensures consistent batch compliance, running HPLC, ICP-MS, and GC-MS analytical screenings on every production lot prior to release.
3. Professional Team: Skilled commercial and technical teams providing proactive guidance and responsive R&D support, assisting brand formulators with dissolution troubleshooting, blend stability, and regulatory filing support.
4. Customer Support: End-to-end service team maintaining close follow-up from inquiry to delivery and beyond to ensure seamless cooperation, providing complete dossier documentation, COAs, MSDS, and customs clearance assistance.
Technical & Commercial FAQ
What is the Minimum Order Quantity (MOQ) for bulk commercial orders?
Standard industrial packaging is 25 Kg per drum. For preliminary laboratory formulation assessments and pilot validation batches, we support sample quantities starting at 1 Kg.
What is the standard manufacturing lead time for large bulk quantities?
We maintain a permanent active warehouse stock of 1,000 Kg to 2,000 Kg ready for dispatch within 48 hours. Scale-up synthesis orders exceeding 5 Metric Tons require 10 to 14 business days.
How does Magnesium L-Threonate compare in aqueous stability to oxide or citrate forms?
Unlike insoluble oxide powders or strongly acidic citrate salts, Magnesium L-Threonate dissolves rapidly in neutral water without altering formulation pH drastically or precipitating out over prolonged storage periods.
What regulatory compliance documentation accompanies dispatched shipments?
All shipped lots arrive with a comprehensive batch Certificate of Analysis (COA), Safety Data Sheet (MSDS), Heavy Metal profile, and ISO22000/HALAL compliance certification. Third-party testing reports are available upon request.
Can NutraJagen provide custom mesh micronization or OEM private labeling?
Yes, we offer custom particle size milling ranging from standard 80 mesh to fine 200 mesh micro-powders for liquid suspensions, along with custom drum labeling, batch coding, and specialized liner options.
Request Factory-Direct Quotation & Pilot Samples
Contact our technical sales team directly to receive tiered volume pricing, request technical dossier documentation, and arrange immediate laboratory sample dispatch.
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