Black Ginger Extract (CAS 56317-21-6) 5,7-Dimethoxyflavone
NutraJagen Black Ginger Extract is a premium ingredient factory-supplied directly for high-standard global formulation requirements.
🧪 Technical Specs: Kaempferia Parviflora Rhizome Extract | Dark Brown to Dark Purple Fine Powder | 5,7-Dimethoxyflavone ≥5.0% HPLC.
📦 MOQ & Packaging: Min Order 1Kg | Standard 25Kg/Drum or Tailored Custom Packaging.
🌍 Global Compliance: Certified by ISO22000, HACCP, and HALAL to meet stringent international audits.
⚡ Supply Capacity: Factory-direct stable bulk supply. Active Stocks: 1,000Kg–2,000Kg available for immediate dispatch. Full COA/MSDS ready.
*Storage Notice: Store in tightly closed original container, protected from light. Free laboratory pilot samples available.
Black Ginger Extract (5,7-Dimethoxyflavone ≥5.0% HPLC)
5,7-Dimethoxyflavone ≥5.0% HPLC (Total PMFs ≥15.0%)
Lipophilic / Soluble in Ethanol & Lipids (Dispersible Options)
MW: 282.29 g/mol | Kaempferia Parviflora Rhizome
Nutraceutical, Sports Nutrition & Functional Food Grade
ISO22000, HACCP, HALAL Certified
Black Ginger Extract (5,7-Dimethoxyflavone 5% HPLC) is a specialized botanical active derived from the cultivated rhizomes of Kaempferia Parviflora (CAS: 56317-21-6), a perennial plant belonging to the Zingiberaceae family. Native raw rhizomes contain wide fluctuations in polymethoxyflavone (PMF) density, causing severe potency variances across raw commercial powders. Supercritical fluid extraction combined with multi-stage column chromatography isolates lipophilic methoxyflavones, standardizing 5,7-dimethoxyflavone strictly to $\ge 5.0\%$ alongside complementary 3,5,7-trimethoxyflavone fractions via validated reverse-phase HPLC-DAD. The resulting dark brown to purple fine powder demonstrates exceptionally low hygroscopicity, preventing sticky clumping during high-speed capsule filling. Formulators integrate this standardized active into pre-workout endurance powders, thermogenic fat burners, and male performance supplements due to its clean crystalline integrity. Bulk procurement ensures complete batch-to-batch chromatographic reproducibility, verified safety against heavy metals, and consistent bioactive performance in demanding retail product launches.
Core Health/Functional Benefits & Commercial Applications
Core Health & Functional Benefits: Methoxyflavones act as direct metabolic modulators by targeting enzyme systems that govern energy expenditure and vascular tone. 5,7-Dimethoxyflavone upregulates AMP-activated protein kinase ($AMPK$) phosphorylation in skeletal muscle and adipocytes. AMPK activation triggers peroxisome proliferator-activated receptor gamma coactivator 1-alpha ($PGC-1\alpha$), accelerating mitochondrial biogenesis and lipid beta-oxidation. Concurrently, polymethoxyflavones exert moderate phosphodiesterase-5 ($PDE5$) enzymatic inhibition. Cyclic guanosine monophosphate ($cGMP$) accumulation within vascular smooth muscle cells promotes nitric oxide ($NO$)-mediated vasodilation, enhancing peripheral blood flow and arterial flexibility. In brown adipose tissue ($BAT$), 5,7-dimethoxyflavone stimulates uncoupling protein 1 ($UCP-1$) expression, increasing non-shivering thermogenesis. Furthermore, the active fraction downregulates inflammatory gene expression by suppressing nuclear factor kappa B ($NF-\kappa B$) signaling, mitigating exercise-induced skeletal muscle damage.
Targeted Industry Applications:
- Sports Performance & Pre-Workout Formulas: Hard gelatin capsules or pre-workout drink mixes formulated at 100mg–150mg daily to enhance physical endurance, stamina, and muscular oxygenation.
- Metabolic & Weight Management Capsules: Thermogenic dietary supplements leveraging AMPK activation to support visceral fat reduction and resting metabolic rate.
- Vascular Health & Male Vitality Products: Botanical vitality complexes combined with L-arginine or citrulline for microvascular nitric oxide synthesis.
- Functional Energy Beverages: Water-dispersible micro-encapsulated powder formulations integrated into ready-to-drink (RTD) performance shots.
- Healthy Aging & Anti-Fatigue Sachets: Nutriceutical stick packs targeting mitochondrial efficiency and chronic fatigue alleviation in active adults.
Technical Specifications (TDS)
| Parameter Item | Testing Standard Specification | Test Method |
|---|---|---|
| Botanical Source / INCI | Kaempferia Parviflora Rhizome Extract | Botanical Identification / TLC |
| CAS Registry Number | 56317-21-6 (5,7-Dimethoxyflavone) | Chemical Reference Directory |
| Physical Appearance | Dark Brown to Dark Purple Fine Powder | Visual Sensory Assessment |
| Active Marker Assay | 5,7-Dimethoxyflavone ≥5.0% (Total PMFs ≥15.0%) | RP-HPLC-DAD (UV at 265nm) |
| Particle Size Distribution | 100% passing 80 Mesh (Sieve size <180 microns) | USP <786> Test Method |
| Loss on Drying & Total Ash | Loss on Drying ≤5.0% | Total Ash ≤5.0% | Gravimetric Analysis (USP <731> / <561>) |
| Heavy Metals Control | Pb ≤2.0ppm, As ≤1.0ppm, Cd ≤1.0ppm, Hg ≤0.1ppm | ICP-MS (Inductively Coupled Plasma) |
| Residual Solvent Control | Ethanol ≤5,000ppm | Hexane & Methanol Non-Detectable | Headspace GC-MS |
| Microbiological Limits | TPC ≤1,000 CFU/g, Yeast & Mold ≤100 CFU/g, Salmonella/E. coli Negative | USP <2021/2022> Microbiological Examination |
| Commercial Packaging | 1kg sealed aluminum foil bags / 25kg fibre drums with dual PE inner liners | Export Industrial Packaging Standard |
| Shelf Life & Storage | 24 Months stored sealed in cool, dry conditions (<25°C) away from light | Real-Time Stability Protocol |
Formulation & Processing Guidelines
- Recommended Daily Dosage: Dietary supplements range from 100mg to 150mg per day of standardized 5% extract, delivering 5mg to 7.5mg of pure 5,7-dimethoxyflavone.
- Thermal Stability Profile: Methoxyflavones demonstrate exceptional heat resistance up to 120°C for short processing durations (under 30 minutes) without chromatographic degradation.
- pH & Matrix Compatibility: Optimal stability occurs between pH 3.0 and 7.0. Naturally hydrophobic polymethoxyflavones blend seamlessly into dry powder matrices, hard shell capsules, or oil suspension softgels.
- Liquid Dispersibility Protocol: Standard powder requires emulsion carriers or solubilizers (such as polysorbates or lecithin) for clear liquid beverages; water-dispersible micro-encapsulated grades are recommended for RTD drinks.
Logistics & Shipping Matrix
| Shipping Method | Suited Volume & Freight Cost | Logistics Service Details |
|---|---|---|
| Express (<50kg) | Pilot Testing & Urgent R&D Batches | Door to Door | 2-3 Days | Dispatched via FedEx/DHL air express. Fully tracked door-to-door delivery with priority customs clearance for laboratory evaluation. |
| Air Freight (>50kg) | Medium Commercial Orders | Airport to Airport | 3-5 Days | Optimal speed-to-cost balance for scheduled manufacturing runs. Temperature-monitored air cargo bays protect active methoxyflavones. |
| Sea Freight (>500kg) | Bulk Industrial Supply | Seaport to Seaport | 5-7 Days (Regional) / 15-25 Days (Global) | Most economical freight method for large-scale tonnage. Palletized 25kg drums receive moisture-proof shrink wraps and desiccant packs. |
Technical & Commercial Advantages
NutraJagen brings more than 15 years of expertise in astaxanthin manufacturing and global supply, backed by a broad portfolio covering thousands of plant extract ingredients engineered for international compliance.
Natural Solutions: Focus on plant-based ingredients aligned with clean, sustainable, and health-oriented international concepts. Raw Kaempferia Parviflora rhizomes originate from controlled cultivation estates adhering to strict GAP agricultural standards.
Quality Management: In-house testing facility combined with independent third-party verification to ensure consistent batch compliance. Advanced RP-HPLC and ICP-MS systems audit every lot for active marker integrity and absolute purity.
Professional Team: Skilled commercial and technical teams providing proactive guidance and responsive R&D support. Senior phytochemical engineers assist formulation scientists with particle dispersion and encapsulation techniques.
Customer Support: End-to-end service team maintaining close follow-up from inquiry to delivery and beyond to ensure seamless cooperation. Complete regulatory packets include full COA, MSDS, allergen statements, and non-irradiation certificates.
Frequently Asked Questions (B2B Commercial)
What is the minimum order quantity (MOQ) for Black Ginger Extract 5%?
Standard commercial MOQ is 1 Kilogram packaged in sealed aluminum vacuum bags. We also accommodate small pilot-scale R&D trial quantities upon request.
What lead time is required for commercial orders exceeding 500kg?
Spot inventory dispatches within 24 to 48 hours. Large-scale custom production batches ship within 7 to 10 working days following final QA release.
How stable are polymethoxyflavones under elevated processing temperatures?
Polymethoxyflavones are highly thermostable. Crystalline 5,7-dimethoxyflavone resists thermal degradation up to 120°C during typical encapsulation and tableting operations.
Which quality and international compliance certificates are available?
Every batch is certified under ISO22000, HACCP, and HALAL standards. Each consignment includes batch COA, MSDS, heavy metal, and pesticide residue test reports.
Can NutraJagen supply water-soluble or custom mesh size options?
Yes. We provide specialized water-dispersible spray-dried grades for beverage applications alongside custom micronization down to 120 mesh for rapid dissolution.
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