Acetyl Tetrapeptide-5 (Eyeseryl / CAS 820959-17-9)
NutraJagen Acetyl Tetrapeptide-5 is a premium ingredient factory-supplied directly for high-standard global formulation requirements.
🧪 Technical Specs: Acetyl Tetrapeptide-5 | White to Off-White Powder | Assay ≥98.0% (HPLC).
📦 MOQ & Packaging: Min Order 0.01Kg | Standard 10g 100g 1Kg/Bag or Tailored Custom Packaging.
🌍 Global Compliance: Certified by ISO22000, HACCP, and HALAL to meet stringent international audits.
⚡ Supply Capacity: Factory-direct stable bulk supply. Active Stocks: 10Kg–20Kg available for immediate dispatch. Full COA/MSDS ready.
*Storage Notice: Store in tightly closed original container, protected from light. Free laboratory pilot samples available.
Acetyl Tetrapeptide-5 (Eyeseryl) Powder ≥98.0% Manufacturer
NutraJagen Acetyl Tetrapeptide-5 represents a specialized synthetic tetrapeptide engineered specifically for targeted dermocosmetic applications addressing periocular tissue congestion. Manufactured via high-precision solid-phase peptide synthesis (SPPS), this high-purity active compound consistently achieves an analytical threshold of ≥98.0%, eliminating unwanted peptide fragments and residual coupling reagents that destabilize final emulsions. Formulators encounter zero dissolution lag due to its exceptional water solubility, making it a robust active component across aqueous serums, cold-process gels, and thick o/w emulsions without disrupting viscosity profiles. By interfering with vascular permeability mechanisms and glycation pathways in dermal matrices, it provides high-tier cosmetic brands with precise, measurable efficacy against eye bag formation and under-eye puffiness, guaranteeing flawless batch-to-batch repeatability and thermal stability required for international commercial scaling.
Core Functional Mechanisms & Target Formulations
1. Core Biological & Physical Benefits
Microvascular Permeability Control: The peptide inhibits Angiotensin-Converting Enzyme (ACE), reducing interstitial fluid accumulation around delicate periocular tissues. Microcirculation optimization halts edematous swelling rapidly.
Anti-Glycation Protection: Prevents non-enzymatic cross-linking of dermal collagen fibers. Retaining collagen elasticity stops skin sagging beneath the lower eyelid margin.
Lipolysis & Dermal Drainage Boost: Accelerates fluid drainage from congested vascular beds, noticeably decreasing dark discoloration linked to stagnant venous blood flow under thin orbital skin.
2. Targeted Industry Applications
Advanced Anti-Puffiness Eye Serums: Primary active ingredient in clear, aqueous gel formulations targeting fluid retention and morning eye bags.
Anti-Dark Circle Repair Creams: Combined with lipid-replenishing agents to strengthen thin skin structure while reducing vascular discoloration under eyes.
Express Recovery Hydrogel Eye Patches: High-solubility profile ensures fast diffusion from polymer matrices into epidermal layers during short-contact application cycles.
Multi-Correction Facial Emulsions: Incorporated into global anti-aging cosmetic lines to treat facial fluid stagnation and loss of dermal firming metrics.
Technical Data Sheet (TDS) & Operational Guidelines
| Parameter | Specification Standard | Test Method |
|---|---|---|
| INCI Name | Acetyl Tetrapeptide-5 | Standard Nomenclature |
| CAS Number | 820959-17-9 | CAS Index |
| Appearance | White to off-white lyophilized powder | Visual Inspection |
| Active Peptide Assay | ≥98.0% | HPLC Analysis |
| Molecular Weight (MW) | 492.5 g/mol | MS |
| Heavy Metals Control | Total ≤ 10 ppm (Pb ≤ 2 ppm, As ≤ 1 ppm) | ICP-MS |
| Residual Solvents | Meets international pharmaceutical limits | GC-HS |
| Microbiological Profile | Total Aerobic Count < 100 CFU/g; Pathogens Negative | USP / EP Standard |
| Commercial Packaging | 100g/bottle, 1kg/aluminum foil bag, 25kg/fiber drum | Standard Export Packaging |
| Shelf Life | 24 Months at 2°C–8°C in sealed original containers | Stability Testing |
Formulation & Handling Guidelines
- Recommended Usage Level: 0.005%–0.05% for pure powder; 1.0%–5.0% for 0.05% liquid solution premixes.
- Thermal Tolerance: Thermal degradation occurs at elevated temperatures. Add to formulations strictly during the cool-down phase at temperatures below 40°C.
- Optimum pH Range: Formulations must maintain a stable pH between 5.0 and 7.0 to prevent peptide hydrolysis.
- Addition Phase: Pre-dissolve pure powder in deionized water before blending into the aqueous phase under mild agitation. Avoid intense high-shear homogenization after peptide introduction.
Global B2B Supply Chain & Shipping Matrix
| Shipping Method | Suited Volume & Freight Cost | Logistics Service Details |
|---|---|---|
| Express Courier (DHL/FedEx/UPS) | < 50kg | Premium Speed, Higher Cost | Door to Door delivery; transit time 2-3 business days. Cold-chain insulated packaging available for temperature-sensitive air shipments. |
| Air Freight | > 50kg | Moderate Freight Cost | Airport to Airport delivery; transit time 3-5 business days. Optimal balance between transit speed and bulk freight efficiency. |
| Sea Cargo | > 500kg | Lowest Unit Freight Cost | Seaport to Seaport delivery; transit time 5-7 days (regional) or 15-30 days (global). Temperature-controlled reefer containers allocated for large volume orders. |
Manufacturing Infrastructure & Corporate Advantages
NutraJagen brings more than 15 years of expertise in astaxanthin manufacturing and global supply, backed by a broad portfolio covering thousands of plant extract ingredients and specialized synthetic cosmetic peptides designed for international contract manufacturers.
Natural Solutions: Focus on plant-based ingredients and high-purity bioactive peptides aligned with clean, sustainable, and health-oriented international formulation concepts.
Quality Management: In-house testing facility equipped with HPLC, GC-MS, and atomic absorption spectrophotometers combined with independent third-party verification to ensure consistent batch compliance.
Professional Team: Skilled commercial and technical teams providing proactive guidance and responsive R&D support tailored to modern global regulatory frameworks.
Customer Support: End-to-end service team maintaining close follow-up from initial inquiry to delivery and beyond to ensure seamless commercial cooperation.
Frequently Asked Questions (Technical & B2B Sourcing)
What is the verified purity and active assay of NutraJagen Acetyl Tetrapeptide-5?
NutraJagen supplies Acetyl Tetrapeptide-5 with a minimum purity of 98.0% verified via High-Performance Liquid Chromatography (HPLC). Every bulk production lot is accompanied by detailed Certificate of Analysis (COA) confirming peptide content, residual solvents, and heavy metal limits.
What is the lead time for 10kg+ commercial orders?
Standard warehouse inventory allows immediate dispatch of 1kg to 10kg within 48 hours. For commercial orders exceeding 10kg, production lead time requires 7 to 10 business days under strict quality controls.
How stable is Acetyl Tetrapeptide-5 in aqueous cosmetic formulations?
Acetyl Tetrapeptide-5 demonstrates excellent chemical stability in aqueous environments across a pH range of 5.0 to 7.0. Formulators should incorporate the ingredient during the cooling phase below 40°C to prevent thermal degradation.
Does NutraJagen provide third-party analytical testing reports?
Yes, independent third-party lab testing reports verifying HPLC purity, heavy metals, micro-contamination, and peptide sequence identity are available upon request for regulatory compliance audits.
Can you supply liquid solution premixes or custom concentrations?
NutraJagen offers specialized solution services, including 0.05% or 0.1% aqueous solutions preserved with formulation-specific preservative systems to fit direct manufacturing production lines.
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