Tripeptide-2 (CAS 17355-22-5)
NutraJagen Tripeptide-2 is a premium ingredient factory-supplied directly for high-standard global formulation requirements.
🧪 Technical Specs: Tripeptide-2 (H-Gly-Pro-Ala-OH) | White Lyophilized Powder | Purity ≥99.0% (HPLC).
📦 MOQ & Packaging: Min Order 10g | Standard 100g, 1Kg/Bottle or Tailored Custom Packaging.
🌍 Global Compliance: Certified by ISO9001, HALAL, and Kosher to meet stringent international audits.
⚡ Supply Capacity: Factory-direct stable bulk supply. Active Stocks: 60Kg–120Kg available for immediate dispatch. Full COA/MSDS ready.
*Storage Notice: Store in tightly closed original container, protected from light. Free laboratory pilot samples available.
Tripeptide-2
Tripeptide-2 is a highly purified synthetic biomimetic peptide comprising glycine, proline, and alanine, designed as an enzymatic protector of the extracellular matrix and a promoter of endogenous structural proteins. Our active material targets the structural degradation of collagen and elastin fibers by suppressing elastase enzymes, effectively restoring the natural tensile strength and firmness of the dermal layer. Synthesized using strict solid-phase protocols, this cosmetic-grade powder resolves typical industry pain points of solubility and temperature-induced denaturation, delivering reliable physical stability during cold-mix compounding. Due to its clean, well-defined molecular structure and low molecular mass, the peptide exhibits superior skin-penetration mechanics and high compatibility with complex gel, serum, and emulsion bases. Incorporating this highly active raw material allows global cosmetics manufacturers and laboratory formulators to develop premium anti-wrinkle solutions with reproducible efficacy, securing a strong market advantage in the anti-aging sector.
Core Benefits & Commercial Applications
Core Structural and Protective Benefits: The primary biological action of Tripeptide-2 involves the targeted inhibition of matrix-degrading enzymes, specifically tissue elastase, which breaks down the skin’s elastic fiber network over time. By preserving existing elastin structures, this peptide maintains the mechanical flexibility and rebound resilience of the skin, preventing premature sagging and fold formation. Fibroblasts exposed to Tripeptide-2 exhibit increased metabolic vitality, leading to optimized secretion of structural glycosaminoglycans and foundational collagen fibers. The small peptide structure also aids in scavenging localized free radicals, mitigating UV-induced inflammatory pathways that trigger accelerated dermal degradation.
Targeted Industry Applications: Formulated as a powerful functional active, Tripeptide-2 is ideally suited for high-tier anti-aging cosmetic lines and specialized dermatological treatments. Its protective properties make it a key active ingredient in structural lifting serums, firming body lotions, and targeted neck creams that counteract gravity-induced sagging. Skincare laboratories utilize this peptide to fortify environmental defense creams, under-eye puffiness solutions, and concentrated wrinkle-filling ampoules. It is also utilized in post-sun recovery formulations to suppress tissue-degrading enzyme spikes caused by UV exposure, helping to preserve the skin’s dermal matrix.
Technical Specifications & Formulation Guidelines
| Parameter | Specification Details |
|---|---|
| INCI Name | Tripeptide-2 |
| CAS Number | 17355-22-5 |
| Sequence | H-Gly-Pro-Ala-OH |
| Appearance | White crystalline powder |
| Purity (HPLC) | ≥99.0% |
| Molecular Weight (MW) | 243.26 g/mol |
| Heavy Metals | ≤10 ppm total (As ≤2 ppm, Pb ≤5 ppm) |
| Moisture (Karl Fischer) | ≤5.0% |
| Microbial Limits | Total Plate Count ≤100 cfu/g, Yeast & Mold ≤10 cfu/g, Pathogens Negative |
| Commercial Packaging | 10g, 100g, 1Kg per high-barrier pharmaceutical-grade bottle |
| Shelf Life | 24 months when stored at 2-8°C in sealed original packaging |
Formulation Processing Parameters: Successful processing of Tripeptide-2 relies on maintaining strict physical conditions within the compounding vessel:
- Recommended Usage Level: Pure powder: 0.005%–0.05% (w/w). Diluted solution (1000 ppm): 0.5%–5.0% (w/w).
- pH Stability Range: Broadly stable within pH 3.5 to 6.5, with optimum chemical stability achieved around pH 5.0 to 6.0.
- Thermal Tolerance: Sensitive to high temperatures. Add strictly during the final cooling phase (below 40°C) of emulsion manufacturing to prevent molecular denaturation.
- Solubility Profile: Highly soluble in water, propylene glycol, and clean glycerol matrices; entirely insoluble in hydrophobic oils and structural lipophilic bases.
Global Logistics & Sea-Air Shipping Matrix
| Shipping Method | Suited Volume & Freight Cost | Logistics Service Details |
|---|---|---|
| Express (DHL/FedEx/UPS) | Best for orders <50kg. Higher unit cost, highly cost-effective for sensitive active ingredients. | Door-to-door expedited delivery, customs clearance managed by carrier, typical transit 2-3 business days globally. |
| Air Freight | Suited for mid-volume batches (50kg to 500kg). Balanced cost structure with fast delivery. | Airport-to-airport transit. Local broker handles import customs, typical transit 3-5 business days. |
| Sea Freight | Suited for heavy bulk orders >500kg. Lowest overall transport cost per kilogram. | Port-to-port delivery. Full container (FCL) or less-than-container (LCL) options, transit times vary between 15-30 days based on port. |
Technical & Commercial Advantages
NutraJagen brings more than 15 years of expertise in astaxanthin manufacturing and global supply, with a broad portfolio covering thousands of plant extract ingredients and advanced biosynthetic cosmetic peptides. We operate on four foundational pillars of business integrity:
- Natural Solutions: We focus on delivering high-performance, plant-based and biomimetic ingredients aligned with clean, sustainable, and health-oriented international concepts, meeting strict eco-responsibility benchmarks.
- Quality Management: Our modern in-house testing facility is backed by independent third-party verification to ensure consistent, traceable batch-to-batch chemical compliance and structural identity.
- Professional Team: Our skilled commercial and technical teams provide proactive regulatory guidance, custom solution development, and highly responsive R&D support.
- Customer Support: A dedicated end-to-end service team maintains close tracking from initial inquiry to final port delivery, establishing frictionless post-sale technical support.
Technical FAQ
What is the minimum commercial order volume (MOQ) for this active peptide powder?
Our factory standards permit a minimum commercial packaging volume starting at 10 grams. We provide trial units of this size to facilitate pilot formulation and testing before committing to large-scale procurement.
What is the typical commercial lead time for dispatching an international air cargo order?
Standard orders of up to 5Kg are prepared and dispatched within 48 hours of payment verification. For large custom synthesized quantities or bulk solutions, our production cycle spans 7 to 14 business days.
What stability data supports the transport and storage of Tripeptide-2?
Our peptide powder remains stable for up to 24 months when kept at 2-8°C. For brief international transit, its robust chemical structure easily tolerates room-temperature conditions without measurable degradation.
Does your manufacturing conform to international cosmetic compliance structures?
Yes, our production operates under verified ISO9001 quality systems. Our material complies with global cosmetic requirements, including the EU, US, and China’s IECIC lists. We provide full regulatory dossiers upon request.
Do you support the manufacturing of pre-dissolved liquid solutions for this peptide?
Yes, we supply customized liquid concentrations (typically 1000 ppm or 5000 ppm) dissolved in high-purity water, glycerin, or butylene glycol matrices. This service offers commercial clients a direct-to-emulsion fluid step during production.
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