Decarboxy Carnosine HCl (Alistin / CAS 57022-38-5)
NutraJagen Decarboxy Carnosine HCl is a premium ingredient factory-supplied directly for high-standard global formulation requirements.
🧪 Technical Specs: Decarboxy Carnosine HCl | Off-White to White Crystalline Powder | Assay ≥98.0% (HPLC).
📦 MOQ & Packaging: Min Order 0.01Kg | Standard 10g 100g 1Kg/Bag or Tailored Custom Packaging.
🌍 Global Compliance: Certified by ISO22000, HACCP, and HALAL to meet stringent international audits.
⚡ Supply Capacity: Factory-direct stable bulk supply. Active Stocks: 10Kg–20Kg available for immediate dispatch. Full COA/MSDS ready.
*Storage Notice: Store in tightly closed original container, protected from light. Free laboratory pilot samples available.
Decarboxy Carnosine HCl (Alistin) Powder ≥98.0% Manufacturer
NutraJagen Decarboxy Carnosine HCl is a high-purity synthetic pseudopeptide molecule designed to provide superior physiological resistance against metabolic degradation in advanced cosmetic formulations. Standard L-carnosine suffers rapid enzymatic cleavage by serum carnosinases. Removing the carboxyl group yields a robust peptidomimetic structure that resists enzymatic cleavage completely. Synthetic synthesis yields a clean assay profile of ≥98.0% by HPLC. Hydrophilic properties grant immediate aqueous dissolution, resolving clarity issues in transparent serum bases. Formulators integrate this compound into anti-aging lines, post-sun recovery products, and environmental pollution shields. High physical stability prevents yellowing and phase separation in complex oil-in-water systems. Batch-to-batch consistency safeguards formulation integrity across global production sites.
Core Functional Mechanisms & Target Formulations
1. Core Health/Functional Benefits
Enzymatic Resistance and Prolonged Bioactivity: Standard carnosine degrades rapidly under tissue carnosinase activity. Eliminating the carboxyl moiety protects the peptide bond from enzymatic cleavage, sustaining long-term cellular protection within dermal layers.
Advanced Glycation End-Product (AGE) Reversal: The molecule acts as a sacrificial nucleophile, trapping reactive carbonyl species (RCS) such as 4-hydroxynonenal (HNE) and malondialdehyde (MDA). Intercepting these intermediates prevents toxic collagen cross-linking and preserves dermal matrix elasticity.
DNA & Membrane Photo-Protection: Exposure to ultraviolet radiation causes singlet oxygen generation and lipid peroxidation. Decarboxy Carnosine HCl neutralizes hydroxyl radicals directly, preventing mitochondrial DNA damage and maintaining cell membrane fluidic stability under oxidative stress.
2. Targeted Industry Applications
Anti-Glycation Firming Serums: Serves as a primary active ingredient in clear, high-potency aqueous treatments targeted at yellowing skin, loss of elasticity, and structural sagging.
Urban Defense & Anti-Pollution Creams: Formulated into day creams and protective shields designed to neutralize environmental heavy metals and particulate-induced oxidative stress.
Post-Procedure & Sun Repair Lotions: Integrated into soothing recovery formulas to attenuate UV-induced erythema, lipid peroxidation, and inflammation cascades.
Targeted Eye Contour Emulsions: Incorporated into delicate periocular care formulations to suppress vascular glycation stress and improve localized tissue tone.
Technical Data Sheet (TDS) & Operational Guidelines
| Parameter | Specification Standard | Test Method |
|---|---|---|
| INCI Name | Decarboxy Carnosine HCl | Standard Nomenclature |
| CAS Number | 57022-38-5 | CAS Index |
| Appearance | Off-white to white crystalline powder | Visual Inspection |
| Assay (Purity) | ≥98.0% | HPLC Analysis |
| Molecular Weight (MW) | 218.68 g/mol | MS |
| Heavy Metals Control | Total ≤ 10 ppm (Pb ≤ 2 ppm, As ≤ 1 ppm) | ICP-MS |
| Residual Solvents | Meets international pharmaceutical limits | GC-HS |
| Microbiological Profile | Total Aerobic Count < 100 CFU/g; Pathogens Negative | USP / EP Standard |
| Commercial Packaging | 1kg/aluminum foil bag, 25kg/fiber drum with double PE bag | Standard Export Packaging |
| Shelf Life | 24 Months at 2°C–8°C in sealed original containers | Stability Testing |
Formulation & Processing Guidelines
- Recommended Addition Dosage: 0.05%–0.2% for pure powder active inclusion; up to 1.0% in intensive anti-glycation concentrate formulas.
- Processing Heat Stability: Thermally stable under brief processing conditions, but late-stage addition during cooling phase (< 40°C) is mandatory to guarantee compound longevity.
- Optimal pH Range: Formulations should be maintained at pH 4.5–6.5. Avoid strongly alkaline environments (> pH 8.0) to prevent degradation of the hydrochloride salt structure.
- Incorporation Method: Dissolve fully in the aqueous phase before emulsification. Compatible with ethanol up to 20% v/v and typical polyols (glycerin, propanediol, butylene glycol).
Global B2B Supply Chain & Shipping Matrix
| Shipping Method | Suited Volume & Freight Cost | Logistics Service Details |
|---|---|---|
| Express Courier (DHL/FedEx/UPS) | < 50kg | Premium Speed, Higher Cost | Door to Door delivery; transit time 2-3 business days. Cold-chain insulated packaging available for temperature-sensitive air shipments. |
| Air Freight | > 50kg | Moderate Freight Cost | Airport to Airport delivery; transit time 3-5 business days. Optimal balance between transit speed and bulk freight efficiency. |
| Sea Cargo | > 500kg | Lowest Unit Freight Cost | Seaport to Seaport delivery; transit time 5-7 days (regional) or 15-30 days (global). Temperature-controlled reefer containers allocated for large volume orders. |
Manufacturing Infrastructure & Corporate Advantages
NutraJagen brings more than 15 years of expertise in astaxanthin manufacturing and global supply, backed by a broad portfolio covering thousands of plant extract ingredients and specialized synthetic pseudopeptides tailored for industrial cosmetic brands.
Natural Solutions: Focus on plant-based ingredients and clean bioactive peptides aligned with clean, sustainable, and health-oriented international formulation concepts.
Quality Management: In-house testing facility equipped with HPLC, GC-MS, and LC-MS systems combined with independent third-party verification to ensure consistent batch compliance.
Professional Team: Skilled commercial and technical teams providing proactive guidance and responsive R&D support tailored to modern global regulatory frameworks.
Customer Support: End-to-end service team maintaining close follow-up from initial inquiry to delivery and beyond to ensure seamless commercial cooperation.
Frequently Asked Questions (Technical & B2B Sourcing)
What minimum order quantity (MOQ) applies to Decarboxy Carnosine HCl commercial orders?
The minimum order quantity for standard commercial supply is 0.01kg sealed in an aluminum foil bag. Large-scale production batches are packaged in 1kg fiber drums with double PE inner liners.
How fast can NutraJagen dispatch 500kg or larger bulk orders?
Active stock levels between 1,000kg and 2,000kg allow dispatch within 48 hours for standard lots. Production lead time for custom batch orders exceeding 500kg ranges from 7 to 10 business days.
What thermal and pH conditions ensure maximum stability during emulsion processing?
Decarboxy Carnosine HCl exhibits superior enzymatic resistance compared to L-carnosine. Maintain processing temperatures under 40°C during late-stage aqueous addition while controlling final formulation pH between 4.5 and 6.5.
Does NutraJagen provide regulatory certification for European and American import audits?
Full batch Certificates of Analysis, MSDS, ISO22000, HACCP, and HALAL documentation accompany all shipments. Heavy metal, residual solvent, and microbiological data meet stringent international requirements.
Can NutraJagen supply pre-dissolved liquid solutions or custom packaging options?
Custom OEM solutions including specific aqueous concentrations (such as 1% or 5% solutions with tailored preservation systems) and customized unit packing sizes are provided upon technical evaluation.
Request Commercial Quote & Free Pilot Samples
Secure factory-direct bulk pricing, download complete regulatory technical dossiers, and request pilot testing samples for your next-generation anti-glycation formulations.
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