Copper Tripeptide-1 (GHK-Cu) Powder | NutraJagen
NutraJagen GHK-Cu Powder (Copper Tripeptide-1) is an ultra-high purity active ingredient designed for premium anti-aging, barrier repair, and advanced scalp care formulations.
- 🧪 Ultra-High Purity: ≥99.0% Assay by HPLC (Batch Typical: 99.7%+).
- 🔬 Verified Specs: Full GHK content ≥70.0% & Copper content 10.0%-16.0% with zero heavy metal anomalies.
- 💧 Excellent Solubility: 100% water-soluble, bluish to bluish-purple crystalline powder.
- 🌍 B2B Readiness: Factory-direct stable bulk supply. Full Batch COA and MSDS documentation ready.
*Free laboratory pilot samples and tiered commercial pricing are available for qualifying formulation brands.
Copper Tripeptide-1 (GHK-Cu) | Premium Cosmetic Peptide Manufacturer
Mechanism of Action & Biological Summary
Structural Matrix Modulation: GHK-Cu acts as a physiological feedback messenger following tissue stress. It contributes to the natural synthesis of type I/III/IV collagens, elastin, and glycosaminoglycans (GAGs), thereby supporting dermal thickness and visible skin elasticity.
Cutaneous Barrier Fortification: It helps modulate the expression of tissue metalloproteinases (MMPs) and their inhibitors (TIMPs). This defensive pathway assists in accelerating micro-injury recovery cycles, making it ideal for post-procedure or sensitive skin applications.
Antioxidant & Cellular Defense: This copper complex plays a significant role in quenching oxidative cascades. By promoting superoxide dismutase (SOD) activity, it assists in neutralizing environmental free radicals, helping mitigate UV-induced premature skin aging.
Follicle Micro-Environment Support: In scalp applications, the complex works to enhance nutrient delivery to the hair roots, helping prolong the anagen phase and complementing advanced thinning-hair formulations.
Technical Reference: GHK-Cu VS AHK-Cu
| Technical Parameters | GHK-Cu (Blue Copper Peptide) | AHK-Cu (Copper Peptide) |
|---|---|---|
| Amino Acid Sequence | Glycine – Histidine – Lysine | Alanine – Histidine – Lysine |
| CAS Number | 89030-95-5 / 49557-75-7 | 682809-81-0 |
| Molecular Formula | C14H21CuN6O4 | C15H24CuN6O4 |
| Primary R&D Target | Deep wrinkle reduction, skin remodeling, barrier repair | Follicle vitalization, scalp care, hair density support |
| Aqueous Solubility | Excellent (>100g/L) | Excellent (>100g/L) |
*Disclaimer: Data presented above is for global technical reference and R&D verification only. Not intended as direct medical claims for consumer-end products.
Technical Specification & Quality Standards
| INCI Name | Copper Tripeptide-1 | Molecular Weight | 400.91 g/mol |
| Appearance | Bluish to bluish purple crystalline powder | Identification | Positive by MS & HPLC |
| Assay (Purity by HPLC) | ≥99.0% | pH (1mg/ml water sol.) | 5.0 ~ 7.0 |
| Water Content | ≤8.0% | Solubility | Easily soluble in water |
| GHK Content | ≥70.0% | Copper Content (Cu) | 10.0% ~ 16.0% |
| Heavy Metals (as Pb) | ≤10 ppm | Arsenic (As) | ≤2 ppm |
| Cadmium (Cd) | ≤5 ppm | Mercury (Hg) | ≤1 ppm |
| Residual Solvents | CH2Cl2 ≤600ppm | CH3CN ≤410ppm | Total Plate Count (TAMC) | ≤1000 cfu/g |
| Molds & Yeasts (TYMC) | ≤100 cfu/g | Pathogens | Negative (E. Coli, Pseudomonas, S. Aureus) |
| Thermal Stability | Stable under recommended storage conditions. Keep tightly sealed, avoid light, seal. | ||
Formulation & Processing Guidelines
- Recommended Concentration: Typically formulated at 0.05% – 0.5% (w/w) for raw pure powder.
- pH Threshold: Finished formulations must strictly maintain a stable pH of 5.0 – 7.0 to prevent complex dissociation.
- Thermal Limitations: Should be introduced during the post-emulsification cooling phase below 40°C.
- Incompatibility Alerts: Incompatible with strong chelators (e.g., EDTA), strong organic acids, high-dose Ascorbic Acid (Vitamin C), Alpha Hydroxy Acids (AHAs), and highly acidic acrylic polymers like traditional Carbomers.
Frequently Asked Questions (FAQ)
1. What is the standard industrial shelf life and storage protocol for GHK-Cu powder?
Our pure Copper Tripeptide-1 powder carries a standard commercial shelf life of 24 months from the manufacturing date. For optimal structural stability, it must be stored in tightly sealed, light-resistant containers at a regulated temperature of 2-8°C.
2. Does NutraJagen supply pre-dissolved liquid copper peptide solutions?
Yes, alongside our primary raw crystalline powder, we provide custom OEM/ODM liquid solutions at standard industry concentrations (e.g., 1000ppm, 2000ppm, or 5000ppm) tailored to specific laboratory formulation requirements.
3. What documentations are available for quality audits?
Every commercial dispatch is accompanied by full regulatory documentation, including the original batch Certificate of Analysis (COA), comprehensive Material Safety Data Sheet (MSDS), heavy metal profiles, and micro-organism clearance certifications.
Get Full Technical Support & Commercial Samples
Accelerate your formulation timeline. Request your specific documentation package today:
- 📋 Batch Certificate of Analysis (COA) & MSDS
- 🔬 Free Laboratory Pilot Sample (Qualifying Brands)
- 💰 Tiered Commercial Bulk Pricing Sheet
- 🧪 R&D Formulation Compatibility Advice
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