Myristoyl Pentapeptide-17 (CAS 959610-30-1)
NutraJagen Myristoyl Pentapeptide-17 is a premium ingredient factory-supplied directly for high-standard global formulation requirements.
🧪 Technical Specs: Myristoyl Pentapeptide-17 | White Crystalline Powder | Assay ≥98.0% (HPLC).
📦 MOQ & Packaging: Min Order 1Kg | Standard 25Kg/Drum or Tailored Custom Packaging.
🌍 Global Compliance: Certified by ISO22000, HACCP, and HALAL to meet stringent international audits.
⚡ Supply Capacity: Factory-direct stable bulk supply. Active Stocks: 1,000Kg–2,000Kg available for immediate dispatch. Full COA/MSDS ready.
*Storage Notice: Store in tightly closed original container, protected from light. Free laboratory pilot samples available.
Myristoyl Pentapeptide-17 (CAS 959610-30-1) Powder ≥98.0% Manufacturer
NutraJagen Myristoyl Pentapeptide-17 is a bio-engineered lipopeptide combining myristic acid with a functional five-amino-acid sequence (Myristoyl-Lys-Leu-Ala-Lys-Lys-NH2) produced via precise solid-phase peptide synthesis to guarantee an assay purity of ≥98.0%. Unmodified hydrophilic peptides encounter strict lipid-barrier resistance along dermal layers. Coupling aliphatic C14 fatty acid chains dramatically enhances transmembrane penetration through follicular epithelium, enabling rapid migration into dermal papilla structures. Advanced solid-phase purification maintains individual peptide impurities below 0.5% while preventing residual coupling agent retention. Cosmetic chemists incorporate this targeted active into high-performance eyelash growth serums, eyebrow density gels, and specialized trichological scalps formulations. Formulators secure verified bioavailability, consistent batch-to-batch solubility, and undeniable performance metrics required by global premium beauty brands.
Core Functional Mechanisms & Target Formulations
1. Core Health/Functional Benefits
Transcriptional Activation of Keratin Genes: Up-regulates human keratin gene expression (specifically KRT14, KRT31, and KRT85) within dermal papilla cells. Increasing structural keratin synthesis thickens individual hair shafts directly at the root zone during active growth phases.
Anagen Phase Extension & Follicle Anchorage: Prolongs the active anagen growing phase of ciliary hair follicles while delaying catagen transition. Stimulating extracellular matrix protein production around the dermal papilla strengthens mechanical hair anchoring, significantly reducing premature lash shedding.
Targeted Follicular Translocation: Conjugating myristoyl fatty acid moieties optimizes the octanol-water partition coefficient. Lipophilic affinity drives efficient penetration into hydrophobic follicular channels without requiring irritating chemical penetration enhancers.
2. Targeted Industry Applications
High-Performance Eyelash Growth Serums: Formulated into clear aqueous or hydrogel lash enhancers at 0.005%–0.01% (or 5%–10% of standard liquid premix solution) to increase lash length, volume, and density.
Eyebrow Densifying Treatments: Blended into targeted brow-thickening gels, conditioning mascaras, and micro-needling post-care solutions aimed at restoring sparse brow lines.
Anti-Hair Loss & Scalp Revitalizing Serums: Integrated into Leave-on scalp tonics, anti-thinning lotions, and bearded care oils designed to strengthen hair roots and combat stress-induced telogen effluvium.
Eyelash Mascara & Primer Infusions: Added into conditioning decorative mascara formulas to provide active lash-strengthening benefits during daily cosmetic wear.
Technical Data Sheet (TDS) & Operational Guidelines
| Parameter | Specification Standard | Test Method |
|---|---|---|
| INCI Name | Myristoyl Pentapeptide-17 | Standard Nomenclature |
| CAS Number | 959610-30-1 | CAS Index |
| Appearance | White to off-white crystalline powder | Visual Inspection |
| Assay (Peptide Purity) | ≥98.0% (Single Impurity ≤ 1.0%) | HPLC |
| Molecular Weight (MW) | 796.10 g/mol | MS / ESI |
| Heavy Metals Control | Total ≤ 10 ppm (Pb ≤ 2 ppm, As ≤ 1 ppm, Cd ≤ 1 ppm) | ICP-MS |
| Residual Solvents | Acetonitrile ≤ 410 ppm, DMF ≤ 880 ppm (Meets EP/USP) | GC-HS |
| Microbiological Profile | Total Plate Count < 100 CFU/g; Pathogens Negative | USP / EP Standard |
| Commercial Packaging | 1kg/vacuum aluminum foil bag, 25kg/fiber drum with dual PE liners | Standard Export Packaging |
| Shelf Life | 24 Months stored in sealed containers protected from light at 2°C–8°C | Stability Testing |
Formulation & Operational Guidelines
- Recommended Dosage: Pure powder active: 0.001%–0.01% (10 ppm to 100 ppm); Liquid premix stock (500 ppm stock solution): 2.0%–10.0% in final finished formulations.
- Thermal Stability Parameters: Sensitive to extended high heat. Heat exposure above 50°C triggers peptide bond hydrolysis. Incorporate during the final cooling phase below 40°C in batch production.
- Optimal pH Range: Maintains optimal chemical structure within pH 5.0 to 7.0. Avoid strong acid (pH < 4.0) or strong base (pH > 8.0) media to prevent amide bond cleavage.
- Phase & Compatibility Notes: Dissolve in water, glycerin, or lyopropylene glycol before blending. Compatible with non-ionic thickeners (e.g., hydroxyethylcellulose), panthenol, and biotinoyl tripeptide-1. Avoid strong anionic surfactant complexes that trigger peptide precipitation.
Global B2B Supply Chain & Shipping Matrix
| Shipping Method | Suited Volume & Freight Cost | Logistics Service Details |
|---|---|---|
| Express Courier (DHL/FedEx/UPS) | < 50kg | Premium Speed, Higher Cost | Door to Door delivery; transit time 2-3 business days. Cold-pack insulated shipping protects peptide structure from extreme temperature spikes during express air cargo delivery. |
| Air Freight | > 50kg | Moderate Freight Cost | Airport to Airport delivery; transit time 3-5 business days. Preferred air solution balancing fast commercial transit with optimized freight tariffs. |
| Sea Cargo | > 500kg | Lowest Unit Freight Cost | Seaport to Seaport delivery; transit time 5-7 days (regional) or 15-30 days (global). Climate-controlled reefer container transport secures peptide stability across ocean transit routes. |
Manufacturing Infrastructure & Corporate Advantages
NutraJagen brings more than 15 years of expertise in astaxanthin manufacturing and global supply, backed by a broad portfolio covering thousands of plant extract ingredients, specialized functional peptides, and high-purity synthetic actives designed for global cosmetic and health industries.
Natural Solutions: Focus on plant-based ingredients and bioactive peptide structures aligned with clean, sustainable, and health-oriented international concepts.
Quality Management: In-house testing facility utilizing LC-MS, HPLC, and ICP-MS combined with independent third-party verification to ensure consistent batch compliance.
Professional Team: Skilled commercial and technical teams providing proactive guidance and responsive R&D support for complex peptide formulations.
Customer Support: End-to-end service team maintaining close follow-up from inquiry to delivery and beyond to ensure seamless commercial cooperation.
Frequently Asked Questions (Technical & B2B Sourcing)
What minimum order quantity (MOQ) applies to Myristoyl Pentapeptide-17 bulk commercial shipments?
Initial evaluation lots start at 0.01kg packaged in light-protected, vacuum-sealed aluminum foil bags. Standard commercial consignments ship in 1kg fiber drums fitted with dual food-grade polyethylene liners.
What dispatch timeline applies to commercial orders exceeding 10kg?
Warehouse reserves maintain 10kg to 20kg available for instant dispatch within 48 hours. Custom synthesis or specific physical solution processing above 10kg requires 7 to 10 working days.
How does lipophilic modification influence the stability and cutaneous delivery of Myristoyl Pentapeptide-17?
Covalent attachment of myristic acid enhances hydrophobic affinity across stratum corneum lipid matrices. This structural alteration prevents premature proteolytic degradation and dramatically boosts follicular uptake.
Which quality compliance documents accompany each batch delivered from the plant?
Every batch dispatches with an official Certificate of Analysis (COA), MSDS, ISO22000, HACCP, and HALAL documentation. Independent third-party lab records verifying heavy metals, residual solvents, and HPLC purity are available on request.
Can NutraJagen supply pre-dissolved liquid masterbatches or custom concentration dilutions?
NutraJagen offers liquid premixes (e.g., 500 ppm aqueous solutions) and customized solvent carrier systems based on client-specific manufacturing requirements.
Request Commercial Quote & Free Pilot Samples
Access direct factory volume pricing, download complete technical dossiers, and request pilot testing samples for your eyelash or trichological formulation projects.
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